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Thrombosis Research
2501 North Orange Avenue
Suite #786
Orlando, FL 32804

Phone: (407) 303-2440 (main office)
Phone: (407) 303-2449 (clinical lab)
Fax: (407) 303-2441

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Tests Available

TEST DESCRIPTION

CPT

SPECIMEN REQUIREMENTS

TEST FREQUENCY

Activated Partial Thromboplastin Time (APTT)

85730

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Daily

Activated Protein C Resistance Screening Test (APCR).

85307

1 BT (see Notes 1 and 2) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml. Send residual cells from BT if separated.

Twice weekly

Alpha-2-Antiplasmin Activity (AP)

85410

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Daily

Anti-b 2 Glycoprotein I (IgG/IgM/IgA) (AB2G)

86146 x 3

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Weekly

Anticardiolipin Antibody (IgG/IgM) (ACA)

86147 x 2

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Weekly

Antiphospholipid Antibody

Antiphosphotidylserine (IgG/IgM) (APA)

86148 x 2

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Weekly

Antithrombin Antigen (AT-Ag)

85301

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Weekly

Antithrombin Activity (AT)

85300

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Twice weekly

Circulating Anticoagulant (see Inhibitor Screen)

Clotting Kinetics (Sonoclot™ Analyzer or Thromboelastography)

85348

1 BT (see Note 3). Minimum volume 5 ml. Call 407-303-2449 to schedule (9 am – 2 pm).

Scheduled (M – F).

Local samples only.

Dilute Russell's Viper Venom Time (DRVVT) See Lupus Anticoagulant Panel

Factor II Activity (FII)

85210

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Daily

Factor II Gene (20210A) Mutation See Prothrombin 20210 Gene Mutation

Factor V Activity (FV)

85220

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Daily

Factor V Leiden (DNA-based test for the FV Leiden gene mutation).

83891
83896x4
83908
83912

1 BT (see Note 2). Residual cells from separated BT are also suitable.

Weekly

Factor VII Activity (FVII)

85230

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

 

Daily

Factor VIII Activity (FVIII)

85240

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Daily

Factor VIII Inhibitor (Bethesda, Human)

(Please note that we no longer offer a test for porcine FVIII inhibitor

85335

1 BT (see Note 1) or 2.0 ml FROZEN plasma. Minimum volume 1.5 ml.

Daily

Factor IX Activity (FIX)

85250

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Daily

Factor X Activity (FX)

85260

 

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Daily

 

Factor X Activity (FX; Chromogenic Assay)

85260

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

M, W, F

Factor XI Activity (FXI)

85270

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Daily

Factor XII Activity (FXII)

85280

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Daily

Factor XIII Screening Test (FXIII)

85291

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Daily

Factor Inhibitor (other than FVIII) (Bethesda, Human). Please specify Factor II, V, VII, XI or XII.

85335

1 BT (see Note 1) or 2.0 ml FROZEN plasma. Minimum volume 1.0 ml.

Daily

Fibrinogen

85384

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Daily

Fletcher Factor (Prekallikrein) Activity

85292

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Weekly

Heparin Antibody

86022

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Daily

Heparin Assay (anti-FXa) low molecular weight heparin (LMWH, Lovenox)

85520

1 BT (see note 4) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Daily

Heparin Assay (anti-FXa) unfractionated heparin (UFH)

85520

1 BT (see note 4) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Daily

Hepzyme™ Treatment (removal of heparin before testing)

85525

n/a

n/a

Hexagonal Phase Phospholipid Neutralization Procedure See Staclot™-LA

Inhibitor Screen (Mixing Study), PT

85610

85611

1 BT (see Note 1) or 2.0 ml FROZEN plasma. Minimum volume 1.5 ml.

Daily

Inhibitor Screen (Mixing Study), APTT

85732 x 5

1 BT (see Note 1) or 2.0 ml aliquots of FROZEN plasma. Minimum volume 1.5 ml.

Daily

Lupus Anticoagulant Panel

DRVVT (Dilute Russell's Viper Venom Time)

PTT-LA

KCT (Kaolin Clot Time)

 

85613

85730

85730

1 BT (see Note 6) or 2.0 ml FROZEN plasma. Minimum volume 1.0 ml.

Twice Weekly

Methyleneltetrahydrafolate Reductase (MTHFR). DNA test for the G677T (thermolabile) gene mutation

83891
83896x4
83908
83912

1 BT (see Note 2). Residual cells from separated BT are also suitable.

Weekly

Plasminogen Activity

85420

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Weekly

Plasminogen Activator Inhibitor activity (PAI-1)

85400

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Weekly

Platelet Aggregation and ATP release profile (includes high and low dose Ristocetin)

85576 x 7

4 BT (see Note 3). Minimum volume 10 ml whole blood. Call (407) 303-2449 to schedule (9 am – 2 pm).

Daily (M – F). Local samples only.

Platelet Antibody Screen – Indirect (HPA-1a, 1b, -3a, -3b, -5a, -5b, GpIb/IX, GpIV and HLA Class I)

86022

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

x3 weekly

Platelet Antibody Screen – Direct (HPA-1a, 1b, -3a, -3b, -5a, -5b, GpIb/IX, GpIV and HLA Class I)

86022

4 BT (see Note 3). Minimum volume 10.0 ml whole blood, but depends on platelet count. Call (407) 303-2449 for advice.

Weekly

Platelet flow cytometry

GpIb - Bernard Soulier Syndrome

GpIIb/IIIa - Glanzmann's Thrombasthenia

 

88184

88185

1 BT (see Note 3). Minimum volume 5 ml whole blood. Call (407) 303-2449 to schedule (9 am – 2 pm).

Daily (M – F)

Local samples only.

Platelet Function Analyzer (PFA-100®)

Collagen/Epinephrine (CEPI)

Collagen/ADP (CADP)

 

85576

85576

2 BT (see Note 3). Minimum volume 5.0 ml whole blood.

Daily M-F 6a – 5p;

Weekends 8a - 4p

Local samples only.

Platelet Neutralization Procedure (PNP) See Staclot™-LA

Protein C Activity

85303

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Twice weekly

Protein C Antigen

85302

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Weekly

Protein S Activity

85306

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Twice weekly

Protein S Antigen – Total

85305

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Weekly

Protein S Antigen - Free

85306

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Weekly

Prothrombin Gene Mutation. DNA test for the 20210A gene mutation.

83891
83896x4
83908
83912

1 BT (see Note 2). Residual cells from separated BT are also suitable.

Weekly

Prothrombin Time (PT)

85610

1 BT (see Note 1) or 1.0 ml FROZEN plasma

Daily

PTT-LA (Lupus Anticoagulant sensitive APTT). See Lupus Anticoagulant Panel.

 

 

Reptilase Time (RT)

85635

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Daily

Ristocetin Aggregation (High/Low dose)

85776 x 2

1 BT (see Note 3). Minimum volume 5 ml. Call (407) 303-2449 to schedule (M-F 9 am – 2 pm).

Daily (M-F). Local samples only.

Serotonin Release Assay (SRA)

Please note that this test is only performed by special arrangement with Laboratory Director Dr. John Francis (407-303-2444)

86022 x 2

1 Plain Red Top (no additive) or 2 ml FROZEN serum. Minimum volume 1.0 ml.

Weekly

(test performed by Thrombosis Research staff)

Staclot™ LA (hexagonal phase phospholipid neutralization test for LA)

85730 85597

1 BT (see Note 6) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Daily

Thrombin Time (TT)

85670

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.2 ml.

Daily

Von Willebrand Factor Activity (Ristocetin Cofactor Activity)

85245

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.5 ml.

Weekly

(usually Thursday or Friday)

Von Willebrand Factor Antigen (FVIII-Related Antigen)

85246

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 0.25 ml.

Weekly

(usually Thursday or Friday)

Von Willebrand Factor Multimers (performed at University of Miami).
PLEASE NOTE: If vWF activity is normal or increased, multimer analysis will only be performed by special arrangement with Dr. John Francis at (407) 303-2444.

85247

1 BT (see Note 1) or 1.0 ml FROZEN plasma. Minimum volume 1.0 ml. A separate aliquot of plasma is required for this test.

Results 2-4 weeks

Additional Tests

The Florida Hospital Center for Hemostasis and Thrombosis is constantly updating its test methodology and introducing new procedures. We can offer a number of tests that are not listed above. Please contact us with your specific requirements for availability and pricing.

Panel Testing

For convenience, we offer recommended Coagulation Test Panels for specific clinical indications.

Reflexive Testing

Please note that to better serve our clients and to aid test interpretation, some of our tests include a reflexive testing procedure. Please refer to the appropriate page in our brochure, the back of our test requisition form, or the Reflex Test page for details of our reflexive test protocols.

Please note

The number of Blue Top (BT) tubes stated is based on the use of 5.0 ml glass, 3.2% sodium citrate tubes.