Sonoclot Analysis

The Sonoclot Analyzer is an instrument used for assessing coagulation and platelet function in whole blood or plasma. It is most typically used as a point-of-care device to manage anticoagulant therapy, assess platelet function and control blood product usage during open heart or liver transplant surgery. It is also a useful research tool.

The Sonoclot Analyzer monitors coagulation using a viscoelastic clot detection mechanism in which a disposable plastic probe is immersed in the blood or plasma sample under test. The probe vibrates and any impedance to the probe movement is monitored. The graphs generated are known as the Sonoclot Signature©.

As a clot forms, so the impedance increases. The Sonoclot Analyzer calculates the clotting time as well as the rate at which clotting proceeds. The peak height is related to platelet number and fibrinogen level, while the subsequent downslope is typically the result of clot retraction. The information can be relayed to a printer or computer for further analysis.

The Sonoclot Analyzer may be useful to demonstrate hypercoagulability (usually increased Clot Rate), platelet function defects.and hyperfibrinolysis. However, for these purposes, the test should be considered Investigational at the present time.