Drugs That Affect Hemostasis

There are now numerous agents available that are designed to interact with the hemostatic system. In general, such agents may be divided into those that treat or prevent clotting (thrombosis) and those that treat or prevent bleeding.

This section of our web site will be permanently under construction and information on new agents will be added as it becomes available. We hope that it will be a useful resource for those wishing to obtain more information on the growing number of agents that fall into these categories. Please note that all intended uses and dosages should be confirmed by reference to the product insert or company representative.

Agents that prevent or treat thrombosis

Anti-platelet drugs
- Aspirin
- Clopidigrel (Plavix®)
- Dipyridamole (Aggrenox®)
- Abciximab (ReoPro®)
- Eptifibatide (Integrilin®)
- Tirofiban (Aggrastat®)
Anticoagulant drugs
- Coumadin
- Heparin
- Low Molecular Weight Heparins (LMWH)
- Fondaparinux (Arixtra®)
- Lepirudin (Refludan®)
- Argatroban
- Bivalirudin (Angiomax®)
- Ximelagatran
- Activated Protein C (Xigris®)
- Tissue Factor Pathway Inhibitor
- Tissue Factor Antibody
- Site-Inactivated Factor VII (Factor VIIai)
Thrombolytic agents
- Recombinant Alteplase (Activase®) tissue plasminogen activator (t-PA)
- Tenecteplase (TNKase™) t-PA variant

Agents that prevent or treat bleeding

Clotting factor concentrates
- Recombinant Factor VIIa (NovoSeven®)
- Alphanate FVIII concentrate
- Bioclate FVIII concentrate
- Monoclate-P FVIII concentrate
- Haemate P FVIII and von Willebrand factor concentrate
- Helixate FVIII concentrate
- Hemophil-M FVIII concentrate
- Humate-P FVIII concentrate
- Hyate-C® Porcine FVIII concentrate
- Koate HP FVIII concentrate
- Kogenate FVIII concentrate
- Recombinate FVIII concentrate
- Mononine FIX concentrate
- Fibrogammin P FXIII concentrate
Anti-fibrinolytic agents
- Aprotinin
- Epsilon Aminocaproic Acid
- Tranexamic Acid
DDAVP
- DDAVP® Nasal Spray (desmopressin acetate)