Contract Research
The Florida Hospital Center for Thrombosis Research can provide a variety of clinical laboratory services on a contract basis. These include, but are not limited to, platelet aggregation and other platelet functional assessments, coagulation factor assays, hypercoagulability studies and heparin-PF4 antibody testing.
Please refer to our on-line test listing for complete details of routinely available tests. Additional testing as well as instrument and reagent evaluations for all aspects of clinical coagulation testing are available on request.
For national and international clinical trials, we offer a complete Core Laboratory service for blood coagulation testing, including provision of blood collection kits and data validation.
Our research team is able to conduct a variety of pre-clinical evaluations of potentially anti-metastatic agents - especially anticoagulant drugs - in appropriate experimental models, and test potential therapeutic agents for their effects on platelet and coagulation activation or inhibition.
We have a special interest and expertise in the potential effects of therapeutic monoclonal antibodies on platelet activation and thrombosis. Our laboratory has developed an animal model for testing the pro-thrombotic effects of such agents.
We are happy to work with any client to design a project appropriate for their needs.
Previous and current contract research projects include:
- effect of anti-tissue factor antibodies on experimental metastasis
- development of specific immunoassays
- heparin antibody testing for national clinical trials
- evaluation of blood collection tubes for hemostatic testing
- biocompatibility testing on vascular graft materials
- biochemical characterization of hemostatic agents
- evaluation of new platelet aggregometer
- antiplatelet effects of vasopressin antagonists
- evaluation of new tests for heparin-induced thrombocytopenia
- anti-tumor effects of novel low molecular weight heparin derivatives
- evaluation of the prothrombotic effects of anti-CD40L antibodies
Please contact John Francis Ph.D. for further information and to discuss your specific requirements.
